Closed-loop insulin delivery
نویسندگان
چکیده
منابع مشابه
Closed-loop insulin delivery for treatment of type 1 diabetes
Type 1 diabetes is one of the most common endocrine problems in childhood and adolescence, and remains a serious chronic disorder with increased morbidity and mortality, and reduced quality of life. Technological innovations positively affect the management of type 1 diabetes. Closed-loop insulin delivery (artificial pancreas) is a recent medical innovation, aiming to reduce the risk of hypogly...
متن کاملFeasibility of Outpatient 24-Hour Closed-Loop Insulin Delivery
Studies using outpatient closed-loop insulin delivery for type 1 diabetes have recently been published (1–5). We conducted a 5-day outpatient feasibility study comparing hybrid closed-loop (HCL) to sensor-augmented pump therapy with low-glucose suspend (SAPT1 LGS) in eight patients with type 1 diabetes using an open-label randomized crossover trial design (ACTRN12614001005640). We used theMedtr...
متن کاملClinical experience with an implanted closed-loop insulin delivery system.
AIM To report the first clinical experience with a prototype of implanted artificial beta-cell. METHODS The Long-Term Sensor System project assessed the feasibility of glucose control by the combined implantation of a pump for peritoneal insulin delivery and a central intravenous glucose sensor, connected physically by a subcutaneous lead and functionally by PID algorithms. It was performed i...
متن کاملClosed-Loop Insulin Delivery Using a Subcutaneous Glucose Sensor and Intraperitoneal Insulin Delivery
OBJECTIVE Attempts to build an artificial pancreas by using subcutaneous insulin delivery from a portable pump guided by an subcutaneous glucose sensor have encountered delays and variability of insulin absorption. We tested closed-loop intraperitoneal insulin infusion from an implanted pump driven by an subcutaneous glucose sensor via a proportional-integral-derivative (PID) algorithm. RESEA...
متن کاملModelling endogenous insulin concentration in type 2 diabetes during closed-loop insulin delivery
BACKGROUND Closed-loop insulin delivery is an emerging treatment for type 1 diabetes (T1D) evaluated clinically and using computer simulations during pre-clinical testing. Efforts to make closed-loop systems available to people with type 2 diabetes (T2D) calls for the development of a new type of simulators to accommodate differences between T1D and T2D. Presented here is the development of a m...
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ژورنال
عنوان ژورنال: Nature Reviews Endocrinology
سال: 2010
ISSN: 1759-5029,1759-5037
DOI: 10.1038/nrendo.2010.31